Zymosan-Induced Peritonitis
نویسندگان
چکیده
منابع مشابه
Ouabain Modulates Zymosan-Induced Peritonitis in Mice
Ouabain, a potent inhibitor of the Na(+), K(+)-ATPase, was identified as an endogenous substance. Recently, ouabain was shown to affect various immunological processes. We have previously demonstrated the ability of ouabain to modulate inflammation, but little is known about the mechanisms involved. Thus, the aim of the present work is to evaluate the immune modulatory role of ouabain on zymosa...
متن کاملABCC transporter inhibition reduces zymosan-induced peritonitis.
Inflammatory mediators are released from injured tissues being responsible for the first steps of inflammatory processes. Multidrug efflux transporters, members of the ATP-binding cassette (ABC) family, are ubiquitously expressed. ABCC molecules transport several endogenous substances, including leukotriene C4 (LTC4) and PGE2, which are involved in zymosan-induced inflammation. The present stud...
متن کاملForsythoside A Modulates Zymosan-Induced Peritonitis in Mice.
Acute inflammation is a protective response of the host to physical injury and invading infection. Timely treatment of acute inflammatory reactions is essential to prevent damage to organisms that can eventually lead to chronic inflammation. Forsythoside A (FTA), an active constituent of Forsythia suspensa, has been reported to have anti-inflammatory, antioxidant, and antibacterial properties. ...
متن کاملPeritoneal lymphatic absorption and solute exchange during zymosan-induced peritonitis in the rat.
Lymph flow is elevated in most inflammatory conditions. However, a few previous studies have indicated that peritoneal lymph flow may actually fall during acute peritonitis. This study was performed to explore this issue further and to study the pathophysiology of peritoneal exchange during peritonitis. Therefore, we wanted to assess the total peritoneal clearance (Cl) and the clearance from pe...
متن کاملGeneration of pro-inflammatory and anti-inflammatory cytokines in the gut in zymosan-induced peritonitis.
In major systemic inflammation such as severe peritonitis, various pro-inflammatory cytokines, such as TNF-alpha, IL-1 beta and IL-6, play important roles in the development of multiple organ dysfunction syndrome (MODS). The purpose of this study was to investigate the outflow of pro-inflammatory and anti-inflammatory cytokines from the efferent mesenteric lymphatic vessels under peritonitis. M...
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ژورنال
عنوان ژورنال: Shock
سال: 2016
ISSN: 1073-2322
DOI: 10.1097/shk.0000000000000669